Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GPR6 | P46095 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2289643 | 0.89 | MEN1 (0.39) | KMT2AMAPTGPR6MEN1 | |
| SCHEMBL12420246 | 0.80 | ALB (0.42) | ALDH1A1L3MBTL1SMN1; SMN2GAA | |
| SCHEMBL2290513 | 0.79 | MAPT (0.52) | KMT2AALDH1A1MAPTPOLBGAA | |
| SCHEMBL4393229 | 0.77 | MEN1 (0.39) | KMT2AALDH1A1POLBL3MBTL1USP2 | |
| SCHEMBL4379436 | 0.75 | MEN1 (0.43) | KMT2AALDH1A1GPR6GAAMEN1 | |
| SCHEMBL4379541 | 0.73 | MEN1 (0.41) | KMT2AALDH1A1MAPTPOLBHTT | |
| SCHEMBL2292550 | 0.73 | EPHX2 (0.44) | KMT2AALDH1A1MAPTPOLBGAA | |
| SCHEMBL4379516 | 0.72 | MEN1 (0.40) | KMT2AALDH1A1MAPTPOLBHTT | |
| SCHEMBL4388230 | 0.72 | MEN1 (0.46) | KMT2AALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL4382730 | 0.72 | MEN1 (0.42) | KMT2AGPR6GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164326-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | Euro-Celtique, S.A. (LU) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150447-A1 | AMIDE COMPOUNDS AND THE USE THEREOF | EURO-CELTIQUE S.A. (LU) | 2008-12-11 | — | — | WO | disclosed |