⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14759526 | 0.98 | — | — | |
| SCHEMBL27520450 | 0.80 | KMT2A (0.47) | — | |
| SCHEMBL3618206 | 0.78 | — | — | |
| SCHEMBL112293 | 0.78 | — | — | |
| SCHEMBL6606012 | 0.77 | — | — | |
| SCHEMBL2086499 | 0.76 | — | — | |
| SCHEMBL5187891 | 0.76 | — | — | |
| SCHEMBL27835831 | 0.76 | — | — | |
| Water SCHEMBL27334970 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL6473638 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 312 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4214210-B1 | COMPOUNDS AND COMPOSITIONS AS SPPL2A INHIBITORS | NOVARTIS AG (CH) | 2025-04-09 | — | — | EP | claimed |
| EP-3740481-B9 | DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS | CYTOKINETICS INC (US) | 2024-10-23 | — | — | EP | claimed |
| EP-3740481-B1 | DIHYDROBENZOFURAN AND INDEN ANALOGS AS CARDIAC SARCOMERE INHIBITORS | CYTOKINETICS INC (US) | 2024-06-26 | — | — | EP | claimed |
| US-20240025884-A1 | COMPOUNDS AS GCN2 INHIBITORS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | DONG-A ST CO., LTD. (KR) | 2024-01-25 | — | — | US | claimed |
| EP-3388433-B1 | PHTHALAZINE DERIVATIVES, AND PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI SIMR BIOTECH CO LTD (CN) | 2023-08-30 | — | — | EP | claimed |
| CN-110407839-A | The preparation and application of the triazol heterocycle compound of the structure containing heteroaryl amide | UNIV JIANGXI NORMAL SCI & TECH | 2019-11-05 | — | — | CN | claimed |
| CN-107311995-B | Tricyclic isoxazole class derivative and its preparation method and application | 沈阳药科大学 | 2019-05-17 | — | — | CN | claimed |
| CN-109071543-A | Inhibit the pyridine derivate of RAF kinases and vascular endothelial growth factor receptor, preparation method contains its medical composition and its use | 三进制药株式会社 | 2018-12-21 | — | — | CN | claimed |
| CN-105658655-B | Thieno [2,3-c] pyrans as CFTR conditioning agents | 加拉佩格斯股份有限公司 | 2018-11-13 | — | — | CN | claimed |
| CN-108779084-A | Crystal type (2S, 4R) -5- (5 '-chloro- 2 '-fluoro- [1,1 '-biphenyl] -4- bases) -2- (ethoxyl methyl) -4- (3- hydroxyl isoxazole -5- formamido groups) -2 methyl valeric acids and its purposes | 施万生物制药研发IP有限责任公司 | 2018-11-09 | — | — | CN | claimed |
| CN-1768031-A | hydroxamates as therapeutic agents | AXYS PHARM INC (US) | 2006-05-03 | — | — | CN | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
| EP-0421224-B1 | Process for the preparation of isoxazole-5-carboxylic acid amide derivatives | BASF AG (DE) | 1994-08-24 | — | — | EP | claimed |
| EP-0337263-B1 | ISOXAZOL(ISOTHIAZOLS)-5-CARBOXAMIDES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | claimed |
| US-5080708-A | Herbicides | BASF AKTIENGESELLSCHAFT (DE) | 1992-01-14 | — | — | US | claimed |
| EP-0193131-B1 | 5-ISOXAZOLECARBOXAMIDES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BASF Aktiengesellschaft (DE) | 1989-12-06 | — | — | EP | claimed |