Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 18/20 | 0.48 |
| ▸ | UQCRB | P14927 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2966396 | 0.93 | CCR9 (0.49) | CCR9UQCRBHSD17B2 | |
| SCHEMBL2966378 | 0.93 | CCR9 (0.49) | CCR9UQCRBHSD17B2 | |
| SCHEMBL2966395 | 0.92 | CCR9 (0.49) | CCR9UQCRBHSD17B2 | |
| SCHEMBL2969190 | 0.91 | CCR9 (0.58) | CCR9UQCRBHSD17B2 | |
| SCHEMBL2968105 | 0.90 | CCR9 (0.47) | CCR9UQCRBHSD17B2 | |
| SCHEMBL2979993 | 0.90 | CCR9 (0.47) | CCR9UQCRBHSD17B2 | |
| SCHEMBL15911907 | 0.90 | CCR9 (0.49) | CCR9UQCRB | |
| SCHEMBL2966415 | 0.89 | CCR9 (0.49) | CCR9UQCRB | |
| SCHEMBL2973006 | 0.88 | CCR9 (0.48) | CCR9 | |
| SCHEMBL2966293 | 0.88 | CCR9 (0.48) | CCR9UQCRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170823-A1 | N-(2-(HETARYL)ARYL)ARYLSULFONAMIDES AND N-(2-(HETARYL)HETARYL)ARYLSULFONAMIDES | ChemoCentryx Inc (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2009038847-A1 | N-(2-(HETARYL)ARYL)ARYLSULFONAMIDES AND N-(2-(HETARYL)HETARYL)ARYLSULFONAMIDES | CHEMOCENTRYX, INC. (US) | 2009-03-26 | — | — | WO | disclosed |