Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3637381 | 1.00 | EP300 (0.31) | EP300CSNK1ETBXAS1 | |
| SCHEMBL3637539 | 1.00 | EP300 (0.31) | EP300CSNK1ETBXAS1 | |
| SCHEMBL3632737 | 1.00 | EP300 (0.31) | EP300CSNK1ETBXAS1 | |
| SCHEMBL3639843 | 1.00 | EP300 (0.31) | EP300CSNK1ETBXAS1 | |
| SCHEMBL3640641 | 0.97 | CSNK1E (0.31) | CSNK1E | |
| SCHEMBL3639587 | 0.97 | EP300 (0.31) | EP300TBXAS1 | |
| SCHEMBL3639951 | 0.95 | CSNK1E (0.31) | CSNK1E | |
| SCHEMBL3636495 | 0.95 | EP300 (0.31) | EP300TBXAS1 | |
| SCHEMBL3639685 | 0.90 | CSNK1E (0.31) | CSNK1E | |
| SCHEMBL10367905 | 0.78 | CNR2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2167619-A2 | PYRROLIDINE-2,5-DIONE DERIVATIVES FOR USE IN FRICTION MODIFICATION | Afton Chemical Corporation (US) | 2010-03-31 | — | — | EP | claimed |
| WO-2008157467-A2 | PYRROLIDINE-2,5-DIONE DERIVATIVES FOR USE IN FRICTION MODIFICATION | AFTON CHEMICAL CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |