Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | PDE5A | O76074 | 3/20 | 0.60 |
| ▸ | HTR3A | P46098 | 2/20 | 0.60 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.55 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.55 |
| ▸ | GLA | P06280 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3643239 | 0.95 | HRH4 (0.67) | HRH4KDM4EMAPK1MAPTNPSR1 | |
| Hydrochloric Acid SCHEMBL3638599 | 0.94 | HRH4 (0.65) | HRH4KDM4EMAPK1MAPTNPSR1 | |
| SCHEMBL3644267 | 0.93 | KDM4E (0.66) | HRH4KDM4EMAPK1MAPTNPSR1 | |
| SCHEMBL3642524 | 0.92 | KDM4E (0.67) | HRH4KDM4EMAPK1MAPTNPSR1 | |
| SCHEMBL3640907 | 0.89 | HRH4 (0.78) | HRH4KDM4EMAPK1MAPTNPSR1 | |
| SCHEMBL29777972 | 0.89 | HRH4 (0.78) | HRH4KDM4EMAPK1MAPTNPSR1 | |
| SCHEMBL21225645 | 0.88 | HRH4 (0.80) | HRH4KDM4EMAPK1MAPTNPSR1 | |
| SCHEMBL3639965 | 0.87 | HRH4 (0.60) | HRH4KDM4EMAPK1MAPTNPSR1 | |
| SCHEMBL2592377 | 0.87 | PDE5A (0.77) | HRH4KDM4EMAPK1MAPTNPSR1 | |
| SCHEMBL3639211 | 0.87 | PDE5A (0.77) | HRH4KDM4EMAPK1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173346-A2 | USE OF COMPOUNDS FOR PREPARING ANTI-TUBERCULOSIS AGENTS | Summit Corporation Plc (GB) | 2010-04-14 | — | — | EP | claimed |
| WO-2009001060-A2 | USE OF COMPOUNDS FOR PREPARING ANTI-TUBERCULOSIS AGENTS | SUMMIT CORPORATION PLC (GB) | 2008-12-31 | — | — | WO | claimed |