Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | SI | P14410 | 4/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL362902 | 0.90 | GPBAR1 (0.45) | BRD4ALDH1A1KDM4EHPGDMAPK14 | |
| SCHEMBL364728 | 0.85 | BRD4 (0.42) | BRD4ALDH1A1MGAMGAASI | |
| SCHEMBL370940 | 0.84 | BRD4 (0.41) | BRD4MGAMGAASIMGAM2 | |
| SCHEMBL363956 | 0.84 | BRD4 (0.41) | BRD4MGAMGAASIMGAM2 | |
| SCHEMBL363934 | 0.83 | GPBAR1 (0.47) | BRD4MGAMGAASIMGAM2 | |
| SCHEMBL14896301 | 0.83 | BRD4 (0.48) | BRD4HPGDMGAMGAASI | |
| SCHEMBL364654 | 0.83 | NPC1 (0.43) | BRD4KDM4EMGAMGAASI | |
| SCHEMBL362661 | 0.81 | BRD4 (0.38) | BRD4MGAMGAASIMGAM2 | |
| SCHEMBL1390288 | 0.81 | BRD4 (0.38) | BRD4ALDH1A1KDM4EHPGDMAPK14 | |
| SCHEMBL1390287 | 0.81 | BRD4 (0.38) | BRD4ALDH1A1KDM4EHPGDMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F.HOFFMANN-LA ROCHE AG (CH) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007365-A1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | F. HOFFMANN-LA ROCHE AG (CH) | 2012-01-19 | — | — | WO | disclosed |