Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.66 |
| ▸ | CTSA | P10619 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15949001 | 1.00 | GPBAR1 (0.66) | GPBAR1CTSACNR2MEN1KMT2A | |
| SCHEMBL15949002 | 1.00 | GPBAR1 (0.66) | GPBAR1CTSACNR2MEN1KMT2A | |
| SCHEMBL15949004 | 1.00 | GPBAR1 (0.66) | GPBAR1CTSACNR2MEN1KMT2A | |
| SCHEMBL364478 | 0.92 | GPBAR1 (0.65) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL1389750 | 0.92 | GPBAR1 (0.65) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL363168 | 0.92 | GPBAR1 (0.65) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL1389748 | 0.92 | GPBAR1 (0.65) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL1390247 | 0.92 | GPBAR1 (0.65) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL1389745 | 0.92 | GPBAR1 (0.65) | GPBAR1CTSAPSEN1PSEN2APH1B | |
| SCHEMBL1390244 | 0.92 | GPBAR1 (0.65) | GPBAR1CTSAPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593426-B1 | 1-HYDROXYIMINO-3-PHENYL-PROPANES | HOFFMANN LA ROCHE (CH) | 2014-08-20 | — | — | EP | disclosed |