Methane

Methane

SCHEMBL3650325

C.CCN(CC)CC.O=S(=O)(Cl)Cl

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.31
CA1 P00915 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28524660 0.97 NPSR1 (0.32) NPSR1CA1
SCHEMBL1193934 0.87 KDM4E (0.31) NPSR1CA1
Water SCHEMBL28342395 0.79 NPSR1 (0.36) NPSR1
Lithium Ion SCHEMBL28345918 0.79 NPSR1 (0.36) NPSR1
Water SCHEMBL28345117 0.79 NPSR1 (0.36) NPSR1
Potassium Ion SCHEMBL28342402 0.79 NPSR1 (0.36) NPSR1
Methane SCHEMBL9112044 0.78
SCHEMBL10434526 0.77 CA1 (0.30) CA1
Sulfuric Acid SCHEMBL11137355 0.76 NPSR1 (0.46) NPSR1CA1
Sulfuric Acid SCHEMBL11137352 0.76 NPSR1 (0.46) NPSR1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109563043-A SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 葛兰素史密斯克莱知识产权发展有限公司 2019-04-02 CN disclosed
CN-106470992-B Pyrido [1,2-A] pyrimidinone analogues as PI3K inhibitor 正大天晴药业集团股份有限公司 2018-11-06 CN disclosed
CN-105461711-B Pyrido [1,2-a] pyrimidinone analogues as PI3K inhibitor 正大天晴药业集团股份有限公司 2018-11-06 CN disclosed
CN-103946220-B Inhibitors of baculovirus containing fragment {2- [4- (biphenyl-4-yl) -1H-imidazol-2-yl ] pyrrolidine-1-carbonylmethyl } amine 施万生物制药研发IP有限责任公司 2017-12-22 CN disclosed
EP-2178860-A1 CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE Healthcare AS (NO) 2010-04-28 EP disclosed
WO-2009021947-A1 CHELATORS, PARAMAGNETIC CHELATES THEREOF AND THEIR USE AS CONTRAST AGENTS IN MAGNETIC RESONANCE IMAGING (MRI) GE HEALTHCARE AS (NO) 2009-02-19 WO disclosed
EP-0199324-B1 NEW 2,5-DIARYL TETRYHYDROFURANS AND ANALOGS THEREOF AS PAF ANTAGONISTS MERCK & CO. INC. (US) 1991-10-02 EP disclosed
US-5010100-A Skeletal muscular disorders, hydertensive agents, cardiovascular disorders MERCK & CO. INC. (US) 1991-04-23 US disclosed
EP-0322033-A2 New 2,5-diaryl tetrahydrofurans and analogs thereof as paf antagonists MERCK & CO. INC. (US) 1989-06-28 EP disclosed
EP-0199324-A2 New 2,5-diaryl tetryhydrofurans and analogs thereof as paf antagonists MERCK & CO. INC. (US) 1986-10-29 EP disclosed