Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.44 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALPG | P10696 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2885397 | 0.87 | BCL6 (0.46) | BCL6MAPTTP53KCNN2KCNN3 | |
| SCHEMBL13067901 | 0.87 | BCL6 (0.46) | BCL6MAPTTP53KCNN2KCNN3 | |
| SCHEMBL2890629 | 0.83 | BCL6 (0.53) | BCL6MAPTTP53KCNN2KCNN3 | |
| SCHEMBL2890844 | 0.81 | BCL6 (0.54) | BCL6MAPTTP53KCNN2KCNN3 | |
| SCHEMBL2889491 | 0.80 | BCL6 (0.47) | BCL6MAPTTP53KCNN2KCNN3 | |
| SCHEMBL2891251 | 0.80 | BCL6 (0.51) | BCL6MAPTTP53KCNN2KCNN3 | |
| SCHEMBL2890777 | 0.80 | BCL6 (0.51) | BCL6MAPTTP53KCNN2KCNN3 | |
| SCHEMBL2885622 | 0.78 | BCL6 (0.51) | BCL6MAPTTP53KCNN2KCNN3 | |
| SCHEMBL3651956 | 0.78 | BCL6 (0.44) | BCL6MAPTTP53KCNN2KCNN3 | |
| SCHEMBL2889465 | 0.77 | BCL6 (0.48) | BCL6MAPTTP53KCNN2KCNN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203436-A1 | PYRAZINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009037247-A1 | PYRAZINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2009-03-26 | — | — | WO | disclosed |