Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL3650862

CCN[C@@H](C)C(=O)O.O=C(O)C(F)(F)F

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MME P08473 1/20 0.35
ACE P12821 1/20 0.35
CPA1 P15085 1/20 0.35
ACE2 Q9BYF1 1/20 0.35
DPP8 Q6V1X1 3/20 0.31
DPP7 Q9UHL4 2/20 0.31
DPP4 P27487 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
SIGMAR1 Q99720 1/20 0.31
KDM4E B2RXH2 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
FUCA1 P04066 1/20 0.30
FAAH O00519 1/20 0.30
S1PR2 O95136 1/20 0.30
S1PR1 P21453 1/20 0.30
S1PR3 Q99500 1/20 0.30
S1PR5 Q9H228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL15512853 1.00 MME (0.35) MMEACECPA1ACE2DPP8
SCHEMBL718531 0.87
SCHEMBL718532 0.87
SCHEMBL2794571 0.87
Hydrochloric Acid SCHEMBL1458134 0.84
Hydrochloric Acid SCHEMBL1458136 0.84
Hydrochloric Acid SCHEMBL21065375 0.84 MME (0.41) MMEACECPA1ACE2ALDH1A1
Hydrochloric Acid SCHEMBL21065373 0.84 MME (0.41) MMEACECPA1ACE2ALDH1A1
Hydrochloric Acid SCHEMBL2723572 0.84
Water SCHEMBL28328238 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2391620-B1 ALKYLAMINE-SUBSTITUTED DICYANOPYRIDINE AND AMINO ACID ESTER PRODRUGS THEREOF BAYER IP GMBH (DE) 2014-05-07 EP disclosed
EP-2185552-B1 DIPEPTOID PRODRUGS AND THE USE THEREOF BAYER IP GMBH (DE) 2014-03-12 EP disclosed
EP-2391620-A1 ALKYLAMINE-SUBSTITUTED DICYANOPYRIDINE AND AMINO ACID ESTER PRODRUGS THEREOF Bayer Pharma Aktiengesellschaft (DE) 2011-12-07 EP disclosed
WO-2010086101-A1 ALKYLAMINE-SUBSTITUTED DICYANOPYRIDINE AND AMINO ACID ESTER PRODRUGS THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2010-08-05 WO disclosed
EP-2185552-A1 DIPEPTOID PRODRUGS AND THE USE THEREOF Bayer Schering Pharma AG (DE) 2010-05-19 EP disclosed
WO-2009015811-A1 DIPEPTOID PRODRUGS AND THE USE THEREOF BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2009-02-05 WO disclosed