Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2001211 | 1.00 | CHRM3 (0.61) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2001581 | 0.97 | CHRM3 (0.60) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2002559 | 0.96 | CHRM3 (0.59) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2001882 | 0.86 | CHRM3 (0.68) | CHRM3CHRM2CHRM1 | |
| SCHEMBL3652795 | 0.84 | CHRM3 (0.64) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1998410 | 0.84 | CHRM3 (0.66) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1997752 | 0.84 | CHRM3 (0.64) | CHRM3CHRM2CHRM1 | |
| SCHEMBL2002810 | 0.83 | CHRM3 (0.65) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1998679 | 0.83 | CHRM3 (0.65) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1997223 | 0.82 | CHRM3 (0.59) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197841-A2 | GUANIDINE-CONTAINING COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | Theravance, Inc. (US) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009035542-A2 | GUANIDINE-CONTAINING COMPOUNDS USEFUL AS MUSCARINIC RECEPTOR ANTAGONISTS | THERAVANCE, INC. (US) | 2009-03-19 | — | — | WO | disclosed |