SCHEMBL365160

SCHEMBL365160

O=[N+]([O-])C1(F)C=CC=CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27801237 0.73
SCHEMBL873824 0.70
SCHEMBL3212979 0.70
Ethane SCHEMBL27535133 0.70
SCHEMBL2977955 0.70
SCHEMBL9650655 0.70
SCHEMBL4254172 0.70
SCHEMBL3953572 0.70
SCHEMBL17593230 0.69
SCHEMBL5497808 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106632245-B Nitrogen substituent group phenyl pyrazoles xanthine oxidoreductase inhibitors and preparation and application 华南理工大学 2019-11-15 CN claimed
CN-109970567-A A method of utilizing Oxyfluorfen by-product production Oxyfluorfen 山东侨昌化学有限公司 2019-07-05 CN claimed
CN-109280008-A A method of utilizing Oxyfluorfen by-product production Oxyfluorfen 山东侨昌化学有限公司 2019-01-29 CN claimed
EP-3180334-A1 PROCESS FOR LARGE SCALE PRODUCTION OF N-[4-(1- CYCLOBUTYL PIPERIDIN-4-YLOXY) PHENYL]-2-(MORPHOLIN-4-YL) ACET AMIDE DIHYDROCHLORIDE Suven Life Sciences Limited (IN) 2017-06-21 EP claimed
WO-2016027275-A1 PROCESS FOR LARGE SCALE PRODUCTION OF N-[4-(1- CYCLOBUTYL PIPERIDIN-4-YLOXY) PHENYL]-2-(MORPHOLIN-4-YL) ACET AMIDE DIHYDROCHLORIDE SUVEN LIFE SCIENCES LIMITED (IN) 2016-02-25 WO claimed
CN-104219954-A Benzamide derivatives TRANSLATIONAL GENOMICS RES INST 2014-12-17 CN claimed
EP-3590925-B1 PYRIDINE COMPOUNDS AND THE USES THEREOF PURDUE PHARMA LP (US) 2022-03-30 EP disclosed
CN-110475777-A For treating and preventing new pyrido [2,3-b] benzazolyl compounds of bacterium infection HOFFMANN LA ROCHE 2019-11-19 CN disclosed
CN-105884780-B Polycyclic compound, its pharmaceutical composition and application 上海迪诺医药科技有限公司 2019-11-08 CN disclosed
CN-106572658-B Molecule and relative intermediate, composition and method with certain disinsection efficiencies 美国陶氏益农公司 2019-11-08 CN disclosed
CN-104788430-B The treatment method of pyrazole derivatives calcium release activation calcium channel modulators and non-small cell lung cancer 理森制药股份公司 2019-10-22 CN disclosed
CN-110300590-A TYK2 inhibitor and application thereof 林伯士拉克许米公司 2019-10-01 CN disclosed
CN-106573927-B Oxyclohepten-2-yl-pyrazol-4-yl-heterocyclyl-carboxamide compounds and methods of use 豪夫迈·罗氏有限公司 2019-09-27 CN disclosed
CN-1702097-A Optical polyimide containing isosorbide unit and process for preparing same UNIV TSINGHUA (CN) 2005-11-30 CN disclosed
CN-1702095-A Polyamide containing isosorbide unit and process for preparing same UNIV TSINGHUA (CN) 2005-11-30 CN disclosed
CN-1702071-A Optical diamine monomer containing di-dehydrated-hexitol unit and process for preparing same UNIV TSINGHUA (CN) 2005-11-30 CN disclosed
EP-1531815-A1 GLUCOKINASE ACTIVATORS NOVO NORDISK A/S (DK) 2005-05-25 EP disclosed
US-20040122235-A1 Aryl carbonyl derivatives as therapeutic agents VTV THERAPEUTICS LLC 2004-06-24 US disclosed
WO-2004002481-A1 ARYL CARBONYL DERIVATIVES AS THERAPEUTIC AGENTS NOVO NORDISK A/S (DK) 2004-01-08 WO disclosed
CN-87103693-A Quinoline-3-carboxylic acid derivatives and its preparation and application 1988-03-30 CN disclosed