⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11996703 | 0.80 | — | — | |
| SCHEMBL20917 | 0.72 | — | — | |
| SCHEMBL3644491 | 0.71 | — | — | |
| SCHEMBL15700202 | 0.71 | — | — | |
| SCHEMBL3695772 | 0.70 | — | — | |
| SCHEMBL27592283 | 0.69 | — | — | |
| Ethyne SCHEMBL27627878 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL23577693 | 0.67 | — | — | |
| SCHEMBL18954 | 0.67 | — | — | |
| SCHEMBL301809 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9624271-B2 | Romidepsin solid forms and uses thereof | CELGENE CORPORATION (US) | 2017-04-18 | — | — | US | claimed |
| US-20160060300-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | CELGENE CORP (US) | 2016-03-03 | — | — | US | claimed |
| US-20140336132-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | CELGENE CORP (US) | 2014-11-13 | — | — | US | claimed |
| EP-2593123-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | Celgene Corporation (US) | 2013-05-22 | — | — | EP | claimed |
| US-20120190817-A2 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | CELGENE CORPORATION (US) | 2012-07-26 | — | — | US | claimed |
| WO-2012009336-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | GLOUCESTER PHARMACEUTICALS, INC. (US) | 2012-01-19 | — | — | WO | claimed |
| EP-2593123-B1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | CELGENE CORP (US) | 2019-09-04 | — | — | EP | disclosed |
| US-9624271-B2 | Romidepsin solid forms and uses thereof | CELGENE CORPORATION (US) | 2017-04-18 | — | — | US | disclosed |
| US-9518094-B2 | Romidepsin solid forms and uses thereof | CELGENE CORPORATION (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160060300-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | CELGENE CORP (US) | 2016-03-03 | — | — | US | disclosed |
| US-20150218225-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | CELGENE CORP (US) | 2015-08-06 | — | — | US | disclosed |
| US-8980825-B2 | Romidepsin solid forms and uses thereof | CELGENE CORPORATION (US) | 2015-03-17 | — | — | US | disclosed |
| US-20140336132-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | CELGENE CORP (US) | 2014-11-13 | — | — | US | disclosed |
| US-20140256637-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | CELGENE CORPORATION (US) | 2014-09-11 | — | — | US | disclosed |
| EP-2593123-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | Celgene Corporation (US) | 2013-05-22 | — | — | EP | disclosed |
| US-20120190817-A2 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | CELGENE CORPORATION (US) | 2012-07-26 | — | — | US | disclosed |
| US-20120046442-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | APTUIT, INC. | 2012-02-23 | — | — | US | disclosed |
| WO-2012009336-A1 | ROMIDEPSIN SOLID FORMS AND USES THEREOF | GLOUCESTER PHARMACEUTICALS, INC. (US) | 2012-01-19 | — | — | WO | disclosed |