Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3651719 | 1.00 | HDAC1 (0.62) | HDAC1 | |
| SCHEMBL3504088 | 0.81 | HDAC1 (0.90) | HDAC1 | |
| SCHEMBL3504086 | 0.81 | HDAC1 (0.90) | HDAC1 | |
| SCHEMBL3548314 | 0.76 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL3548312 | 0.76 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL28628801 | 0.76 | NPC1 (0.60) | HDAC1 | |
| SCHEMBL3547842 | 0.72 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL3547846 | 0.72 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL3550877 | 0.70 | HDAC1 (1.00) | HDAC1 | |
| SCHEMBL3550875 | 0.70 | HDAC1 (1.00) | HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195029-A2 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | Oryzon Genomics SA (ES) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009027349-A2 | TREATMENT AND PREVENTION OF NEURODEGENERATIVE DISEASES | ORYZON GENOMICS SA (ES) | 2009-03-05 | — | — | WO | disclosed |