Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL3401199 | 0.61 | KDM4E (0.33) | KDM4ELMNAKMT2A | |
| Sulfuric Acid SCHEMBL28470571 | 0.60 | — | — | |
| Sulfuric Acid SCHEMBL11235635 | 0.59 | — | — | |
| Sulfuric Acid SCHEMBL21195059 | 0.57 | HTT (0.42) | ALDH1A1KDM4ELMNAKMT2A | |
| Sulfuric Acid SCHEMBL1552980 | 0.55 | — | — | |
| Sulfuric Acid SCHEMBL6657 | 0.53 | — | — | |
| Sulfuric Acid SCHEMBL28501412 | 0.53 | TSHR (0.80) | ALDH1A1KDM4ELMNAKMT2ATDP1 | |
| Sulfuric Acid SCHEMBL8192555 | 0.53 | TSHR (0.80) | ALDH1A1KDM4ELMNAKMT2ATDP1 | |
| SCHEMBL9423160 | 0.53 | GRIN2D (0.31) | KMT2ATDP1 | |
| Sulfuric Acid SCHEMBL28001380 | 0.52 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673267-A1 | 1,3-DIOXAN-5-ONE COMPOUNDS | Merck Patent GmbH (DE) | 2013-12-18 | — | — | EP | disclosed |
| WO-2012107158-A1 | 1,3-DIOXAN-5-ONE COMPOUNDS | MERCK PATENT GMBH (DE) | 2012-08-16 | — | — | WO | disclosed |
| EP-2200735-A1 | METHOD FOR THE CONTINUOUS PRODUCTION OF COLORING AGENTS FOR KERATINIC FIBERS | Henkel AG & Co. KGaA (DE) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009053127-A1 | METHOD FOR THE CONTINUOUS PRODUCTION OF COLORING AGENTS FOR KERATINIC FIBERS | HENKEL AG & CO. KGAA (DE) | 2009-04-30 | — | — | WO | disclosed |