Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | PREP | P48147 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21761369 | 0.84 | CHRM2 (0.43) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL7958092 | 0.84 | CHRM2 (0.43) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL2764923 | 0.83 | CHRM2 (0.51) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL23377566 | 0.83 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL29947374 | 0.83 | CHRM2 (0.47) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL9312524 | 0.82 | CHRM2 (0.50) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL19627636 | 0.82 | CHRM2 (0.50) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL8934384 | 0.82 | CHRM2 (0.50) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL19627634 | 0.82 | CHRM2 (0.50) | CHRM2CHRM1CHRM3PREPHPGD | |
| SCHEMBL19634252 | 0.82 | CHRM2 (0.50) | CHRM2CHRM1CHRM3PREPHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010094643-A1 | QUINOLINE DERIVATIVES AND THEIR USES FOR RHINITIS AND URTICARIA | GLAXO GROUP LIMITED (GB) | 2010-08-26 | — | — | WO | disclosed |
| EP-2205585-A1 | QUINOLINE DERIVATIVES USED TO TREAT INFLAMMATORY AND ALLERGIC DISEASES | Glaxo Group Limited (GB) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009050204-A1 | QUINOLINE DERIVATIVES USED TO TREAT INFLAMMATORY AND ALLERGIC DISEASES | GLAXO GROUP LIMITED (GB) | 2009-04-23 | — | — | WO | disclosed |