Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 4/20 | 0.70 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.70 |
| ▸ | THRA | P10827 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | ACP3 | P15309 | 1/20 | 0.54 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | PTPRB | P23467 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | PTEN | P60484 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30765594 | 0.98 | FFAR1 (0.68) | FFAR1FFAR4THRATHRBTAAR1 | |
| SCHEMBL1981615 | 0.90 | FFAR4 (0.59) | FFAR1FFAR4THRATHRBTAAR1 | |
| SCHEMBL11755472 | 0.89 | HDAC1 (0.60) | FFAR1FFAR4THRATHRBTAAR1 | |
| SCHEMBL8491974 | 0.88 | TAAR1 (0.61) | FFAR1FFAR4THRATHRBTAAR1 | |
| SCHEMBL27689330 | 0.87 | FFAR4 (0.60) | FFAR1FFAR4THRATHRBTAAR1 | |
| SCHEMBL7150587 | 0.87 | MAPT (0.60) | FFAR1FFAR4THRATHRBTAAR1 | |
| SCHEMBL10684837 | 0.85 | FFAR1 (0.54) | FFAR1FFAR4THRATHRBKEAP1 | |
| SCHEMBL16575624 | 0.85 | TAAR1 (0.57) | FFAR1FFAR4THRATHRBTAAR1 | |
| SCHEMBL1509 | 0.85 | TAAR1 (0.57) | FFAR1FFAR4THRATHRBTAAR1 | |
| SCHEMBL185922 | 0.85 | TAAR1 (0.62) | FFAR1FFAR4THRATHRBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118459357-A | Refining method of cinacalcet hydrochloride drug intermediate | 山东威高药业股份有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118184679-A | Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material | 中国石油天然气股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-115551846-B | 1,4,5, 6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2024-03-08 | — | — | CN | claimed |
| WO-2023085396-A1 | PHARMACEUTICAL COMPOSITION FOR PROVIDING TREATMENT FOR OR PREVENTING ALPORT SYNDROME | ＵＢＥ株式会社 | 2023-05-19 | — | — | WO | claimed |
| CN-115551846-A | 1,4,5,6-tetrahydropyrimidin-2-amine derivatives | ＵＢＥ株式会社 | 2022-12-30 | — | — | CN | claimed |
| CN-110167933-B | As αVAzole amides and amines as integrin inhibitors | 百时美施贵宝公司 | 2022-06-21 | — | — | CN | claimed |
| CN-107963965-A | The preparation method of m-trifluoromethyl benzenpropanoic acid | 常州市阳光药业有限公司 | 2018-04-27 | — | — | CN | claimed |
| CN-104892356-B | The preparation method of m-trifluoromethyl phenylpropanol | 常州市阳光药业有限公司 | 2017-10-17 | — | — | CN | claimed |
| CN-104478736-B | A kind of preparation method of cinacalcet hydrochloride | 成都启泰医药技术有限公司 | 2016-07-13 | — | — | CN | claimed |
| EP-2403823-B1 | PROCESS FOR THE PREPARATION OF CINACALCET AND SALTS THEREOF, AND INTERMEDIATES FOR USE IN THE PROCESS | CIPLA LTD (IN) | 2015-10-21 | — | — | EP | claimed |
| WO-2010100429-A1 | PROCESS FOR THE PREPARATION OF CINACALCET AND SALTS THEREOF, AND INTERMEDIATES FOR USE IN THE PROCESS | CIPLA LIMITED (IN) | 2010-09-10 | — | — | WO | claimed |
| EP-2170805-A2 | METHODS OF SYNTHESIZING CINACALCET AND SALTS THEREOF | Amgen Inc. (US) | 2010-04-07 | — | — | EP | claimed |
| EP-1915335-B1 | PROCESS FOR THE PREPARATION OF CINACALCET BASE | TEVA PHARMA (IL) | 2009-11-04 | — | — | EP | claimed |
| WO-2009002427-A2 | METHODS OF SYNTHESIZING CINACALCET AND SALTS THEREOF | AMGEN INC. (US) | 2008-12-31 | — | — | WO | claimed |
| EP-1990333-A1 | Process for the preparation of cinacalcet hydrochloride | Sandoz AG (CH) | 2008-11-12 | — | — | EP | claimed |
| US-7449603-B2 | Process for the preparation of cinacalcet base | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2008-11-11 | — | — | US | claimed |
| EP-1915335-A2 | PROCESS FOR THE PREPARATION OF CINACALCET BASE | Teva Pharmaceutical Industries Ltd (IL) | 2008-04-30 | — | — | EP | claimed |
| WO-2008035381-A2 | PROCESS FOR THE PREPARATION OF AMINE DERIVATIVES AS CALCIMIMETICS | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-03-27 | — | — | WO | claimed |
| WO-2007127445-A2 | PROCESS FOR THE PREPARATION OF CINACALCET BASE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2007-11-08 | — | — | WO | claimed |
| US-20070259964-A1 | Process for the preparation of cinacalcet base | TEVA PHARMACEUTICALS USA, INC. | 2007-11-08 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259964-A1 | Process for the preparation of cinacalcet base | KRAS, CA9, CA4 | FFAR1 4083/4885FFAR4 3356/4885THRA 4419/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.