Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 20/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656201 | 0.90 | BDKRB1 (0.76) | BDKRB1 | |
| SCHEMBL3814285 | 0.87 | BDKRB1 (0.63) | BDKRB1 | |
| SCHEMBL13908578 | 0.87 | BDKRB1 (0.63) | BDKRB1 | |
| SCHEMBL1712831 | 0.81 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL3653969 | 0.77 | CYP3A4 (0.52) | BDKRB1 | |
| SCHEMBL20236214 | 0.75 | EPHX2 (0.47) | BDKRB1 | |
| SCHEMBL13908812 | 0.75 | BDKRB1 (0.52) | BDKRB1 | |
| SCHEMBL1723742 | 0.74 | BDKRB1 (0.65) | BDKRB1 | |
| SCHEMBL1723744 | 0.74 | BDKRB1 (0.73) | BDKRB1 | |
| SCHEMBL1713332 | 0.74 | BDKRB1 (0.76) | BDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2195288-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | Jerini AG (DE) | 2010-06-16 | — | — | EP | disclosed |
| WO-2009036996-A2 | SMALL MOLECULE BRADYKININ B1 RECEPTOR ANTAGONISTS | JERINI AG (DE) | 2009-03-26 | — | — | WO | disclosed |