Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3657076 | 0.94 | FFAR1 (0.85) | FFAR1 | |
| SCHEMBL16326357 | 0.93 | FFAR1 (0.76) | FFAR1 | |
| SCHEMBL2506484 | 0.92 | FFAR1 (0.87) | FFAR1 | |
| SCHEMBL2502827 | 0.92 | FFAR1 (0.87) | FFAR1 | |
| SCHEMBL26979024 | 0.89 | FFAR1 (0.69) | FFAR1 | |
| SCHEMBL29377453 | 0.89 | FFAR1 (0.69) | FFAR1 | |
| SCHEMBL27128599 | 0.89 | FFAR1 (0.69) | FFAR1 | |
| SCHEMBL3654845 | 0.88 | FFAR1 (0.75) | FFAR1 | |
| SCHEMBL2500729 | 0.87 | FFAR1 (0.73) | FFAR1 | |
| SCHEMBL2499261 | 0.87 | FFAR1 (0.73) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205548-A1 | SUBSTITUTED BIPHENYL GPR40 MODULATORS | Amgen, Inc (US) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009048527-A1 | SUBSTITUTED BIPHENYL GPR40 MODULATORS | AMGEN INC. (US) | 2009-04-16 | — | — | WO | disclosed |