Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17800120 | 1.00 | GAA (0.31) | GAASLC6A4SLC6A3 | |
| SCHEMBL6703558 | 1.00 | GAA (0.31) | GAASLC6A4SLC6A3 | |
| SCHEMBL2449769 | 0.98 | GAA (0.31) | GAA | |
| SCHEMBL2345264 | 0.93 | — | — | |
| SCHEMBL9787725 | 0.83 | SLC6A4 (0.31) | SLC6A4SLC6A3 | |
| SCHEMBL1692296 | 0.82 | — | — | |
| SCHEMBL27449789 | 0.80 | SLC6A4 (0.34) | SLC6A4SLC6A3 | |
| SCHEMBL24329981 | 0.79 | GAA (0.31) | GAA | |
| SCHEMBL5245937 | 0.79 | CDC25A (0.35) | — | |
| SCHEMBL11903723 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203163-A1 | TITRATION PACKAGE FOR NERAMEXANE AND ITS USE IN THE TREATMENT OF AN INNER EAR DISORDER | Merz Pharma GmbH & Co. KGaA (DE) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009033651-A1 | TITRATION PACKAGE FOR NERAMEXANE AND ITS USE IN THE TREATMENT OF AN INNER EAR DISORDER | MERZ PHARMA GMBH & CO. KGAA (DE) | 2009-03-19 | — | — | WO | disclosed |