Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BDKRB2 | P30411 | 3/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL28440529 | 0.95 | — | — | |
| Ethane SCHEMBL28353493 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL487532 | 0.80 | — | — | |
| Alcohol SCHEMBL2443956 | 0.78 | — | — | |
| Ethyl Chloride SCHEMBL27638545 | 0.78 | — | — | |
| Butane SCHEMBL27529761 | 0.78 | HRH3 (0.43) | HRH3SMN1; SMN2TP53ALDH1A1CYP3A4 | |
| Ethylamine SCHEMBL1615923 | 0.78 | — | — | |
| Butane SCHEMBL28006675 | 0.78 | HRH3 (0.43) | HRH3SMN1; SMN2TP53ALDH1A1CYP3A4 | |
| Benzidine SCHEMBL25422776 | 0.78 | TDP1 (0.73) | SMN1; SMN2TP53ALDH1A1CYP3A4LMNA | |
| Benzidine SCHEMBL6160242 | 0.78 | TDP1 (0.73) | SMN1; SMN2TP53ALDH1A1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023886-B2 | (R)-selective amination | PATHEON HOLDINGS I B.V. (NL) | 2018-07-17 | — | — | US | disclosed |
| CN-103189519-B | (R) -Selective amination | DPx控股有限公司 | 2018-01-26 | — | — | CN | disclosed |
| EP-2593556-B1 | ENZYMATIC METHOD FOR (R)-SELECTIVE AMINATION | DPX HOLDINGS BV (NL) | 2017-08-30 | — | — | EP | disclosed |
| US-20160032335-A1 | (R)- SELECTIVE AMINATION | DPX HOLDINGS B.V. (NL) | 2016-02-04 | — | — | US | disclosed |
| CN-103189519-A | (R) -Selective amination | DSM IP ASSETS BV | 2013-07-03 | — | — | CN | disclosed |
| EP-2593556-A1 | (R)-SELECTIVE AMINATION | DSM IP Assets B.V. (NL) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007548-A1 | (R)-SELECTIVE AMINATION | DSM IP ASSETS B.V. (NL) | 2012-01-19 | — | — | WO | disclosed |