Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.35 |
| ▸ | LDLR | P01130 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658672 | 0.91 | MAPT (0.36) | LMNAMAPTGAASMOTP53 | |
| SCHEMBL303610 | 0.83 | SMO (0.40) | SMO | |
| SCHEMBL302292 | 0.80 | SMO (0.43) | SMO | |
| SCHEMBL1922432 | 0.78 | SMO (0.41) | SMO | |
| SCHEMBL1923378 | 0.78 | SMO (0.43) | SMO | |
| SCHEMBL3626429 | 0.78 | LDLR (0.45) | LMNAMAPTGAALDLRTP53 | |
| SCHEMBL302505 | 0.77 | SMO (0.43) | SMO | |
| SCHEMBL1921698 | 0.77 | SMO (0.40) | SMO | |
| SCHEMBL1922090 | 0.77 | SMO (0.42) | SMO | |
| SCHEMBL1921989 | 0.77 | SMO (0.42) | SMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010027746-A2 | HEDGEHOG PATHWAY MODULATORS | IRM LLC (BM) | 2010-03-11 | — | — | WO | disclosed |