Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104439 | 0.88 | BTK (0.77) | BTKCLK2 | |
| SCHEMBL107656 | 0.88 | BTK (0.69) | BTKCLK2 | |
| SCHEMBL9985437 | 0.83 | BTK (0.79) | BTKCLK2 | |
| SCHEMBL103784 | 0.83 | BTK (0.67) | BTKCLK2 | |
| SCHEMBL2492566 | 0.83 | BTK (0.60) | BTKCLK2 | |
| SCHEMBL3804473 | 0.82 | BTK (0.63) | BTKCLK2 | |
| SCHEMBL1779482 | 0.82 | BTK (0.65) | BTKCLK2 | |
| SCHEMBL107601 | 0.81 | BTK (0.60) | BTKCLK2 | |
| SCHEMBL105988 | 0.81 | BTK (0.64) | BTKCLK2 | |
| SCHEMBL105574 | 0.81 | BTK (0.66) | BTKCLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2205564-A1 | NOVEL KINASE INHIBITORS | F. Hoffmann-Roche AG (CH) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009053269-A1 | NOVEL KINASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-04-30 | — | — | WO | disclosed |