Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6524805 | 0.92 | CNR1 (0.39) | ARCNR1PGR | |
| SCHEMBL1974760 | 0.92 | CNR1 (0.43) | ARCNR1PGR | |
| SCHEMBL6519999 | 0.92 | CNR1 (0.43) | ARCNR1PGR | |
| SCHEMBL6521558 | 0.91 | CNR1 (0.42) | ARCNR1PGR | |
| SCHEMBL1975686 | 0.91 | CNR1 (0.42) | ARCNR1PGRHDAC1 | |
| SCHEMBL1973173 | 0.91 | CNR1 (0.50) | ARCNR1 | |
| SCHEMBL6523498 | 0.90 | AR (0.37) | ARCNR1PGR | |
| SCHEMBL1973862 | 0.89 | CNR1 (0.41) | ARCNR1PGR | |
| SCHEMBL8021094 | 0.88 | CNR1 (0.40) | ARCNR1PGRHDAC1 | |
| SCHEMBL3523761 | 0.84 | AR (0.40) | ARPGRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2252591-A1 | ARYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | Sanofi-Aventis (FR) | 2010-11-24 | — | — | EP | disclosed |
| WO-2009097999-A1 | ARYL-SUBSTITUTED IMIDAZOLIDINE-2,4-DIONES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |