SCHEMBL3660115

SCHEMBL3660115

N#Cc1cc[nH]c1N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2787313 0.72
SCHEMBL12728673 0.70
SCHEMBL5174113 0.70
SCHEMBL29127602 0.70
SCHEMBL8614804 0.70
SCHEMBL194923 0.70
SCHEMBL8617390 0.70
SCHEMBL6098812 0.69 CCR8 (0.35)
SCHEMBL3251199 0.67
SCHEMBL25447541 0.66 DYRK1A (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119638703-A Synthesis method of 7H-pyrrolo [2,3-d ] pyrimidine-4-amine 台州职业技术学院 2025-03-18 CN claimed
CN-107778208-A A kind of preparation method of polysubstituted pyrrole compound 湖南华腾制药有限公司 2018-03-09 CN claimed
CN-105503878-A Synthesis method of anagliptin HAIMEN BAIKANG PHARMACEUTICAL CO LTD 2016-04-20 CN claimed
US-20050198745-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-09-15 US claimed
US-20260028342-A1 ENHANCING ANTIMETASTASIS ACTIVITY USING TARGETED PROTEIN DEGRADATION UNIV NORTH CAROLINA CHAPEL HILL (US) 2026-01-29 US disclosed
WO-2025245472-A1 COMPOUNDS AND RELATED METHODS USEFUL FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES REMIX THERAPEUTICS INC. (US) 2025-11-27 WO disclosed
CN-119638703-A Synthesis method of 7H-pyrrolo [2,3-d ] pyrimidine-4-amine 台州职业技术学院 2025-03-18 CN disclosed
CN-119638703-A Synthesis method of 7H-pyrrolo [2,3-d ] pyrimidine-4-amine 台州职业技术学院 2025-03-18 CN disclosed
US-20240279231-A1 MAP4K4 INHIBITORS AND METHODS OF SYNTHESIS AND USE THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2024-08-22 US disclosed
EP-4352221-A1 MAP4K4 INHIBITORS AND METHODS OF SYNTHESIS AND USE THEREOF The Board Of Regents Of The University Of Oklahoma (US) 2024-04-17 EP disclosed
WO-2024026064-A1 ENHANCING ANTIMETASTASIS ACTIVITY USING TARGETED PROTEIN DEGRADATION THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2024-02-01 WO disclosed
CN-116178376-A Synthesis method of Pevonedistit intermediate 山东莱福科技发展有限公司 2023-05-30 CN disclosed
CN-1128755-A Intermediate for synthesis of pesticide RHONE POULENC AGROCHIMIE (FR) 1996-08-14 CN disclosed
EP-0708090-A1 Intermediates useful for the synthesis of pesticides RHONE-POULENC AGROCHIMIE (FR) 1996-04-24 EP disclosed
WO-1996010028-A1 PYRROLO[2,3-d]PYRIMIDINES AND THEIR USE NOVARTIS AG (CH) 1996-04-04 WO disclosed
EP-0669927-A1 SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS ANTIVIRALS INC. (US) 1995-09-06 EP disclosed
WO-1995019774-A1 BICYCLIC COMPOUNDS CAPABLE OF INHIBITING TYROSINE KINASES OF THE EPIDERMAL GROWTH FACTOR RECEPTOR FAMILY WARNER-LAMBERT COMPANY (US) 1995-07-27 WO disclosed
US-5405938-A Hydrogen bonding an N-heterocyclic-substituted ribose-based polymer to a double-stranded DNA to block genetic activity, to diagnose for pathogens and to aid in genetic engineering ANTI-GENE DEVELOPMENT GROUP (US) 1995-04-11 US disclosed
WO-1994012517-A1 SEQUENCE-SPECIFIC BINDING POLYMERS FOR DUPLEX NUCLEIC ACIDS ANTIVIRALS INC. (US) 1994-06-09 WO disclosed
US-5166315-A Polynucleotides for genetic engineering ANTI-GENE DEVELOPMENT GROUP (US) 1992-11-24 US disclosed