Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5582741 | 0.82 | S1PR4 (0.40) | S1PR4TRIM24TRIM33NPC1RAB9A | |
| SCHEMBL30020489 | 0.82 | S1PR4 (0.41) | S1PR4TRIM24TRIM33NPC1RAB9A | |
| SCHEMBL68709 | 0.82 | S1PR4 (0.41) | S1PR4TRIM24TRIM33NPC1RAB9A | |
| SCHEMBL31651666 | 0.76 | S1PR4 (0.50) | S1PR4TRIM24TRIM33NPC1RAB9A | |
| SCHEMBL25791866 | 0.75 | S1PR4 (0.46) | S1PR4TRIM24TRIM33NPC1RAB9A | |
| SCHEMBL2861434 | 0.74 | MEN1 (0.46) | S1PR4TRIM24TRIM33SMN1; SMN2LMNA | |
| SCHEMBL9980697 | 0.73 | S1PR4 (0.55) | S1PR4TRIM24TRIM33NPC1RAB9A | |
| SCHEMBL25794980 | 0.72 | S1PR4 (0.44) | S1PR4TRIM24TRIM33NPC1RAB9A | |
| SCHEMBL5582737 | 0.69 | S1PR4 (0.41) | S1PR4TRIM24TRIM33NPC1RAB9A | |
| SCHEMBL30640674 | 0.69 | S1PR4 (0.41) | S1PR4TRIM24TRIM33NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2593432-A1 | N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS | Pfizer Limited (GB) | 2013-05-22 | — | — | EP | disclosed |
| WO-2012007861-A1 | N-SULFONYLBENZAMIDE DERIVATIVES USEFUL AS VOLTAGE GATED SODIUM CHANNEL INHIBITORS | PFIZER LIMITED (GB) | 2012-01-19 | — | — | WO | disclosed |