SCHEMBL36606

SCHEMBL36606

C=CCC(O)OC(=O)C(=C)C

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5245923 0.80 TSHR (0.44) TSHRALDH1A1THRB
SCHEMBL28497162 0.79
SCHEMBL16592838 0.79 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL8966139 0.79 TSHR (0.45) TSHRALDH1A1THRB
SCHEMBL28391183 0.78 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL11414241 0.78 TSHR (0.38) TSHRALDH1A1THRB
SCHEMBL690396 0.77 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL5152027 0.77 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL28531896 0.77 TSHR (0.37) TSHRALDH1A1THRB
SCHEMBL10439986 0.77 TSHR (0.43) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8895669-B2 Method for producing ABA-triblock copolymers with a bimodal B-block EVONIK ROEHM GMBH (DE) 2014-11-25 US disclosed
US-8829117-B2 Method for producing ABA-triblock copolymers with a widely distributed B-block EVONIK ROEHM GMBH (DE) 2014-09-09 US disclosed
US-8802785-B2 Process for preparing AB diblock copolymers with a bimodally distributed A block EVONIK RÖHM GMBH (DE) 2014-08-12 US disclosed
US-20110282007-A1 METHOD FOR PRODUCING ABA-TRIBLOCK COPOLYMERS WITH A WIDELY DISTRIBUTED B-BLOCK HENKEL AG & CO. KGAA (DE) 2011-11-17 US disclosed
US-20110269913-A1 METHOD FOR PRODUCING TELECHELICS HAVING A WIDE MOLECULAR WEIGHT DISTRIBUTION HENKEL AG & CO. KGAA (DE) 2011-11-03 US disclosed
US-20110224359-A1 PROCESS FOR PREPARING AB DIBLOCK COPOLYMERS WITH A BIMODALLY DISTRIBUTED A BLOCK Evonik Riehm GmbH (DE) 2011-09-15 US disclosed
US-20110213091-A1 METHOD FOR PRODUCING TELECHELICS HAVING A BIMODAL MOLECULAR WEIGHT DISTRIBUTION EVONIK ROEHM GMBH (DE) 2011-09-01 US disclosed
US-20110207876-A1 METHOD FOR PRODUCING ABA-TRIBLOCK COPOLYMERS WITH A BIMODAL B-BLOCK EVONIK ROEHM GMBH (DE) 2011-08-25 US disclosed