Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 9/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | GCG | P01275 | 1/20 | 0.38 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.36 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3111104 | 0.90 | DDR1 (0.44) | PPARDGCGRDDR1EPHX2CNR1 | |
| SCHEMBL3100296 | 0.87 | DDR1 (0.45) | PPARDGCGRDDR1EPHX2CNR1 | |
| SCHEMBL3107244 | 0.85 | PPARD (0.44) | PPARDGCGRDDR1EPHX2CNR1 | |
| SCHEMBL3113330 | 0.85 | DDR1 (0.41) | PPARDGCGRDDR1EPHX2CNR1 | |
| SCHEMBL3115892 | 0.85 | DDR1 (0.43) | PPARDDDR1EPHX2CNR1CNR2 | |
| SCHEMBL3108216 | 0.84 | PPARD (0.42) | PPARDGCGRDDR1EPHX2CNR1 | |
| SCHEMBL3102420 | 0.84 | CNR1 (0.41) | PPARDGCGRDDR1EPHX2CNR1 | |
| SCHEMBL3114614 | 0.83 | DDR1 (0.44) | PPARDDDR1EPHX2CNR1CNR2 | |
| SCHEMBL3112367 | 0.83 | CNR1 (0.42) | PPARDGCGREPHX2CNR1CNR2 | |
| SCHEMBL3111640 | 0.83 | CNR1 (0.44) | PPARDGCGRDDR1EPHX2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2209768-A1 | 5,6-DIARYL PYRIDINES SUBSTITUTED IN THE 2- AND 3-POSITION, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | Sanofi-Aventis (FR) | 2010-07-28 | — | — | EP | disclosed |
| WO-2009087285-A1 | 5,6-DIARYL PYRIDINES SUBSTITUTED IN THE 2- AND 3-POSITION, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2009-07-16 | — | — | WO | disclosed |