⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28482557 | 0.73 | HTR2C (0.43) | — | |
| SCHEMBL5618588 | 0.70 | HTR2C (0.55) | — | |
| SCHEMBL5619702 | 0.70 | HTR2C (0.55) | — | |
| SCHEMBL5618115 | 0.70 | HTR2C (0.55) | — | |
| SCHEMBL995422 | 0.68 | HTR2C (0.41) | — | |
| SCHEMBL995419 | 0.68 | HTR2C (0.41) | — | |
| SCHEMBL2943826 | 0.68 | HTR2C (0.41) | — | |
| SCHEMBL29977318 | 0.67 | — | — | |
| SCHEMBL25429547 | 0.67 | HTR2C (0.38) | — | |
| Hydrochloric Acid SCHEMBL18149760 | 0.67 | HTR2C (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217583-A1 | BENZENESULFONANILIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR | Abbott GmbH & Co. KG (DE) | 2010-08-18 | — | — | EP | disclosed |
| US-7569690-B2 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2009-08-04 | — | — | US | disclosed |
| WO-2009056632-A1 | BENZENESULFONANILIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR | ABBOTT GMBH & CO. KG (DE) | 2009-05-07 | — | — | WO | disclosed |
| US-20060161003-A1 | Process for producing oxycarbonyl-substituted piperazine derivative | TORAY FINE CHEMICALS CO., LTD. (JP) | 2006-07-20 | — | — | US | disclosed |
| EP-1548010-A1 | PROCESS FOR PRODUCING OXYCARBONYL-SUBSTITUTED PIPERAZINE DERIVATIVE | Toray Fine Chemicals Co., Ltd. (JP) | 2005-06-29 | — | — | EP | disclosed |
| JP-2004115510-A | METHOD FOR PRODUCING PIPERAZINE DERIVATIVE | TORAY FINE CHEMICALS CO LTD | 2004-04-15 | — | — | JP | disclosed |