SCHEMBL3661152

SCHEMBL3661152

C#CCCCCOc1cccc(NC)c1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.48
MAOB P27338 13/20 0.45
MAOA P21397 5/20 0.44
KDM1A O60341 1/20 0.43
THRB P10828 1/20 0.41
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CA12 O43570 2/20 0.39
CA9 Q16790 2/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3663588 0.98 APP (0.47) APPMAOBMAOAKDM1ATHRB
SCHEMBL3660450 0.98 APP (0.47) APPMAOBMAOAKDM1ATHRB
SCHEMBL3660168 0.95 APP (0.49) APPMAOBMAOAKDM1ATHRB
SCHEMBL3660250 0.91 APP (0.50) APPMAOBMAOAKDM1ATHRB
SCHEMBL3659405 0.84 APP (0.47) APPMAOBTHRBMEN1KMT2A
SCHEMBL3662533 0.82 APP (0.46) APPMAOBTHRBKMT2ATSHR
SCHEMBL3662742 0.82 APP (0.46) APPMAOBTHRBTSHR
SCHEMBL3661921 0.81 APP (0.53) APPMAOBMAOACA12CA9
SCHEMBL28203171 0.80 TSHR (0.61) APPTHRBKMT2ATSHR
SCHEMBL27342972 0.80 TSHR (0.61) APPTHRBKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHIEMCAL COMPANY LIMITED (JP) 2010-12-09 US disclosed
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100311790-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME ATL3, NAT1, C5 APP 2380/4885MAOB 667/4885MAOA 735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.