Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.43 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.43 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3634596 | 1.00 | NAALAD2 (0.46) | NAALAD2GRIN2DGRIN3BGRIN1GRIN2A | |
| Trifluoroacetic Acid SCHEMBL952655 | 0.80 | DPP4 (0.44) | NAALAD2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL24251553 | 0.78 | NAALAD2 (0.60) | NAALAD2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL31696740 | 0.78 | NAALAD2 (0.60) | NAALAD2GRIN2DGRIN3BGRIN1GRIN2A | |
| Trifluoroacetic Acid SCHEMBL953473 | 0.77 | P2RY12 (0.42) | NAALAD2LMNAPLA2G2C | |
| SCHEMBL21063724 | 0.71 | GRIN2D (0.49) | NAALAD2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL1891365 | 0.66 | GRIA2 (0.50) | NAALAD2L3MBTL1ALDH1A1LMNAKDM6B | |
| SCHEMBL1891367 | 0.66 | GRIA2 (0.50) | NAALAD2L3MBTL1ALDH1A1LMNAKDM6B | |
| SCHEMBL5325383 | 0.63 | NAALAD2 (0.49) | NAALAD2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL2433629 | 0.63 | NAALAD2 (0.56) | NAALAD2GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238128-B1 | HETEROCYCLIC PYRAZOLE-CARBOXAMIDES AS P2Y12 ANTAGONISTS | SANOFI SA (FR) | 2012-08-22 | — | — | EP | disclosed |
| EP-2238128-A2 | HETEROCYCLIC PYRAZOLE-CARBOXAMIDES AS P2Y12 ANTAGONISTS | Sanofi-Aventis (FR) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009080226-A2 | HETEROCYCLIC PYRAZOLE-CARBOXAMIDES AS P2Y12 ANTAGONISTS | SANOFIS-AVENTIS (FR) | 2009-07-02 | — | — | WO | disclosed |