⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16084768 | 0.83 | — | — | |
| SCHEMBL3763612 | 0.83 | — | — | |
| SCHEMBL10790289 | 0.77 | — | — | |
| SCHEMBL14942610 | 0.72 | — | — | |
| SCHEMBL8674649 | 0.72 | — | — | |
| SCHEMBL6842946 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL9471658 | 0.68 | — | — | |
| SCHEMBL1200380 | 0.62 | — | — | |
| Carbon Tetrachloride SCHEMBL3648805 | 0.61 | — | — | |
| Carbon Tetrachloride SCHEMBL8874630 | 0.61 | TSHR (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227482-A1 | 2',4'-SUBSTITUTED NUCLEOSIDES AS ANTIVIRAL AGENTS | Pharmasset, Inc. (US) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009067409-A1 | 2',4'-SUBSTITUTED NUCLEOSIDES AS ANTIVIRAL AGENTS | PHARMASSET, INC. (US) | 2009-05-28 | — | — | WO | disclosed |