Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL952072 | 0.93 | P2RY12 (0.71) | P2RY12 | |
| SCHEMBL952073 | 0.93 | P2RY12 (0.71) | P2RY12 | |
| SCHEMBL3659332 | 0.93 | P2RY12 (0.54) | P2RY12 | |
| SCHEMBL955256 | 0.86 | P2RY12 (0.80) | P2RY12 | |
| SCHEMBL955259 | 0.86 | P2RY12 (0.80) | P2RY12 | |
| SCHEMBL952088 | 0.86 | P2RY12 (0.64) | P2RY12 | |
| SCHEMBL952089 | 0.86 | P2RY12 (0.64) | P2RY12 | |
| SCHEMBL3663422 | 0.85 | P2RY12 (0.66) | P2RY12 | |
| SCHEMBL953883 | 0.85 | P2RY12 (0.68) | P2RY12 | |
| SCHEMBL953885 | 0.85 | P2RY12 (0.68) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238128-A2 | HETEROCYCLIC PYRAZOLE-CARBOXAMIDES AS P2Y12 ANTAGONISTS | Sanofi-Aventis (FR) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009080226-A2 | HETEROCYCLIC PYRAZOLE-CARBOXAMIDES AS P2Y12 ANTAGONISTS | SANOFIS-AVENTIS (FR) | 2009-07-02 | — | — | WO | disclosed |