⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5699515 | 0.75 | — | — | |
| SCHEMBL3086538 | 0.75 | — | — | |
| SCHEMBL8705308 | 0.75 | — | — | |
| SCHEMBL5558986 | 0.75 | — | — | |
| SCHEMBL5699553 | 0.75 | — | — | |
| SCHEMBL17675472 | 0.71 | — | — | |
| SCHEMBL5962341 | 0.70 | — | — | |
| SCHEMBL5971945 | 0.70 | — | — | |
| SCHEMBL7154176 | 0.70 | — | — | |
| SCHEMBL12085241 | 0.68 | IDO1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604305-B1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | WAKUNAGA PHARMA CO LTD (JP) | 2024-08-28 | — | — | EP | disclosed |
| CN-110520422-B | Novel pyridonecarboxylic acid derivative or salt thereof | 涌永制药株式会社 | 2023-09-05 | — | — | CN | disclosed |
| US-11286255-B2 | Pyridone carboxylic acid derivative or salt thereof | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2022-03-29 | — | — | US | disclosed |
| US-20200062752-A1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | WAKUNAGA PHARMACEUTICAL CO., LTD. (JP) | 2020-02-27 | — | — | US | disclosed |
| EP-3604305-A1 | NOVEL PYRIDONE CARBOXYLIC ACID DERIVATIVE OR SALT THEREOF | Wakunaga Pharmaceutical Co., Ltd. (JP) | 2020-02-05 | — | — | EP | disclosed |
| US-8278454-B2 | Process for preparing tetrahydroquinoline derivatives | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2012-10-02 | — | — | US | disclosed |
| US-8278454-B2 | Process for preparing tetrahydroquinoline derivatives | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 2012-10-02 | — | — | US | disclosed |
| US-20100311976-A1 | PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-09 | — | — | US | disclosed |
| US-20100311976-A1 | PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MERCK PATENT GESELLSCHAFT (DE) | 2010-12-09 | — | — | US | disclosed |
| EP-2220067-A2 | PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | Merck Patent GmbH (DE) | 2010-08-25 | — | — | EP | disclosed |
| EP-2220067-A2 | PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | Merck Patent GmbH (DE) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009077052-A3 | PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009077052-A2 | PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-06-25 | — | — | WO | disclosed |
| WO-2009077052-A2 | PROCESS FOR PREPARING TETRAHYDROQUINOLINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2009-06-25 | — | — | WO | disclosed |
| US-4171356-A | 2-Unsubstituted derivatives of 4,6-di-o-(aminoglycosyl)-1,3-diaminocyclitois, methods for their use as antibacterial agents and compositions useful therefor | SCHERING CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-3995044-A | Pyridine carboxylic acid amides for mycobacterium infections | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-30 | — | — | US | disclosed |