Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | TYR | P14679 | 3/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662096 | 0.78 | TYR (0.47) | CES2TYRHSP90AB1CA12CA1 | |
| SCHEMBL13206600 | 0.77 | TYR (0.42) | TYRHSP90AB1ALDH1A1GFERCA12 | |
| SCHEMBL13206599 | 0.77 | TYR (0.42) | TYRHSP90AB1ALDH1A1GFERCA12 | |
| SCHEMBL3662538 | 0.76 | ESR1 (0.47) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL16836085 | 0.74 | TYR (0.46) | CES2TYRALDH1A1CA12CA1 | |
| SCHEMBL19444459 | 0.74 | TYR (0.48) | CES2TYRALDH1A1CA12CA1 | |
| SCHEMBL28861491 | 0.72 | MAOB (0.45) | TYRHSP90AB1CA12CA1CA2 | |
| SCHEMBL28218108 | 0.70 | TTR (0.47) | TYRGFER | |
| SCHEMBL10404681 | 0.69 | HSP90AB1 (0.47) | CES2TYRHSP90AB1ALDH1A1CA12 | |
| SCHEMBL19444291 | 0.69 | TYR (0.44) | CES2TYRALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2219600-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009067095-A1 | TOPICAL COSMETIC SKIN LIGHTENING COMPOSITIONS AND METHODS OF USE THEREOF | STIEFEL LABORATORIES, INC. (US) | 2009-05-28 | — | — | WO | disclosed |