Toluene Diisocyanate

Toluene Diisocyanate

SCHEMBL3662949

CCC.Cc1ccc(N=C=O)cc1N=C=O

nearest known ligand 0.89

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.89
TRPA1 O75762 1/20 0.89
TDP1 Q9NUW8 3/20 0.44
MAPK1 P28482 2/20 0.44
TSHR P16473 2/20 0.42
ALDH1A1 P00352 2/20 0.38
LMNA P02545 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
USP2 O75604 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
HPGD P15428 1/20 0.36
CYP1A2 P05177 1/20 0.36
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene Diisocyanate SCHEMBL19733056 0.94 CYP3A4 (1.00) CYP3A4TRPA1TDP1MAPK1TSHR
Toluene Diisocyanate SCHEMBL28174227 0.94 CYP3A4 (1.00) CYP3A4TRPA1TDP1MAPK1TSHR
Toluene Diisocyanate SCHEMBL29737260 0.94 CYP3A4 (1.00) CYP3A4TRPA1TDP1MAPK1TSHR
Toluene Diisocyanate SCHEMBL15384 0.94 CYP3A4 (1.00) CYP3A4TRPA1TDP1MAPK1TSHR
Toluene Diisocyanate SCHEMBL29350148 0.94 CYP3A4 (1.00) CYP3A4TRPA1TDP1MAPK1TSHR
Toluene Diisocyanate SCHEMBL28794223 0.93 CYP3A4 (0.83) CYP3A4TRPA1TDP1MAPK1TSHR
Toluene Diisocyanate SCHEMBL11209945 0.92 CYP3A4 (0.96) CYP3A4TRPA1TDP1MAPK1TSHR
Toluene Diisocyanate SCHEMBL4905176 0.92 CYP3A4 (0.96) CYP3A4TRPA1TDP1MAPK1TSHR
Toluene Diisocyanate SCHEMBL6219230 0.92 CYP3A4 (0.96) CYP3A4TRPA1TDP1MAPK1TSHR
Toluene Diisocyanate SCHEMBL20897289 0.92 CYP3A4 (0.96) CYP3A4TRPA1TDP1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2121303-B1 MULTI-LAYERED FILM AND FLOCKED MATERIAL COMPRISING SUCH A FILM DIMONTONATE FLOCCATI S P A (IT) 2010-07-14 EP claimed
EP-2121303-A1 MULTI-LAYERED FILM AND FLOCKED MATERIAL COMPRISING SUCH A FILM Dimontonate Floccati S.p.A. (IT) 2009-11-25 EP claimed
WO-2008087672-A1 MULTI-LAYERED FILM AND FLOCKED MATERIAL COMPRISING SUCH A FILM DIMONTONATE FLOCCATI S.P.A. (IT) 2008-07-24 WO claimed
CN-109917507-A The manufacturing method of polarizability stacked film and the manufacturing method of polarizing film 住友化学株式会社 2019-06-21 CN disclosed
CN-107037523-B Polaroid and polarizer comprising the polaroid 住友化学株式会社 2019-06-07 CN disclosed
CN-107703578-B Polarizer 住友化学株式会社 2019-03-01 CN disclosed
CN-109254342-A Polarizing film 住友化学株式会社 2019-01-22 CN disclosed
CN-105814463-B Polaroid and polarizer comprising the polaroid 住友化学株式会社 2019-01-22 CN disclosed
CN-105793747-B Polarizer and polarizing plate comprising same 住友化学株式会社 2018-12-11 CN disclosed
CN-107703578-A polarizer 住友化学株式会社 2018-02-16 CN disclosed
CN-105683788-B Polarizing plate 住友化学株式会社 2017-10-10 CN disclosed
EP-2121303-B1 MULTI-LAYERED FILM AND FLOCKED MATERIAL COMPRISING SUCH A FILM DIMONTONATE FLOCCATI S P A (IT) 2010-07-14 EP disclosed
EP-2121303-A1 MULTI-LAYERED FILM AND FLOCKED MATERIAL COMPRISING SUCH A FILM Dimontonate Floccati S.p.A. (IT) 2009-11-25 EP disclosed
WO-2008087672-A1 MULTI-LAYERED FILM AND FLOCKED MATERIAL COMPRISING SUCH A FILM DIMONTONATE FLOCCATI S.P.A. (IT) 2008-07-24 WO disclosed
CN-101160364-A Patterned adhesives for color shifting effect 3M INNOVATIVE PROPERTIES CO (US) 2008-04-09 CN disclosed
US-7270877-B2 Protective tape used for optical member NITTO DENKO CORPORATION (JP) 2007-09-18 US disclosed
US-7160611-B2 Pressure sensitive adhesive optical film and image viewing display NITTO DENKO CORPORATION (JP) 2007-01-09 US disclosed
US-20040151903-A1 Protective tape used for optical member NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-08-05 US disclosed
US-20030198807-A1 Pressure sensitive adhesive optical film and image viewing display NITTO DENKO CORPORATION (JP) 2003-10-23 US disclosed
US-5795650-A MULTILAYER ELEMENT WITH ACRYLIC ADHESIVES FOR LIQUID CRYSTAL DISPLAYS LINTEC CORPORATION (JP) 1998-08-18 US disclosed