Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | QPCT | Q16769 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL592289 | 0.84 | GRM2 (0.34) | KCNH2TRPV1POLB | |
| SCHEMBL592386 | 0.84 | GRM2 (0.34) | KCNH2TRPV1POLB | |
| SCHEMBL3658469 | 0.84 | GRM2 (0.34) | KCNH2TRPV1POLB | |
| SCHEMBL589977 | 0.78 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL589978 | 0.78 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL589979 | 0.78 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL2172185 | 0.77 | HPGD (0.32) | KCNH2TRPV1 | |
| SCHEMBL12096170 | 0.75 | HTT (0.39) | TRPV1POLB | |
| SCHEMBL591984 | 0.73 | GRM2 (0.36) | POLB | |
| SCHEMBL590379 | 0.73 | GRM2 (0.36) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2225242-A2 | DERIVATIVES OF N-HETEROCYCLIC-IMIDAZOÝ1,2-A¨PYRIDINE-2-CARBOXAMIDES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | Sanofi-Aventis (FR) | 2010-09-08 | — | — | EP | disclosed |
| EP-2146987-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-27 | — | — | EP | disclosed |
| WO-2009106749-A2 | DERIVATIVES OF N-HETEROCYCLIC-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXAMIDES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI-AVENTIS (FR) | 2009-09-03 | — | — | WO | disclosed |
| WO-2008126024-A2 | OXAZOLIDINONE ANTIBIOTIC DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |