Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 14/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663394 | 1.00 | FFAR1 (0.42) | FFAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3870789 | 1.00 | FFAR1 (0.42) | FFAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3870787 | 1.00 | FFAR1 (0.42) | FFAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3665499 | 0.89 | FFAR1 (0.43) | FFAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3665498 | 0.89 | FFAR1 (0.43) | FFAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13715327 | 0.89 | CYP2D6 (0.35) | FFAR1MEN1KMT2A | |
| SCHEMBL3547644 | 0.88 | FFAR1 (0.41) | FFAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3547642 | 0.88 | FFAR1 (0.41) | FFAR1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3545039 | 0.88 | FFAR1 (0.38) | FFAR1MEN1KMT2A | |
| SCHEMBL3545038 | 0.88 | FFAR1 (0.38) | FFAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139843-A1 | SUBSTITUTED BIPHENYL PHENOXY-, THIOPHENYL- AND AMINOPHENYLPROPANOIC ACID GPR40 MODULATORS | Amgen, Inc (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008130514-A1 | SUBSTITUTED BIPHENYL PHENOXY-, THIOPHENYL- AND AMINOPHENYLPROPANOIC ACID GPR40 MODULATORS | AMGEN INC. (US) | 2008-10-30 | — | — | WO | disclosed |