Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5399209 | 0.94 | — | — | |
| Maleic Acid SCHEMBL3663487 | 0.79 | TSHR (0.35) | — | |
| SCHEMBL8777769 | 0.65 | — | — | |
| SCHEMBL184925 | 0.63 | — | — | |
| SCHEMBL5272284 | 0.63 | — | — | |
| SCHEMBL2145978 | 0.63 | — | — | |
| SCHEMBL17956810 | 0.63 | — | — | |
| Iodide SCHEMBL11371216 | 0.61 | — | — | |
| SCHEMBL8689309 | 0.59 | — | — | |
| SCHEMBL5783318 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231648-A1 | NEW SALTS AND CRYSTAL FORMS | BIAL - Portela & Ca., S.A. (PT) | 2010-09-29 | — | — | EP | claimed |
| WO-2009072915-A1 | NEW SALTS AND CRYSTAL FORMS | BIAL - PORTELA & CA., S.A. (PT) | 2009-06-11 | — | — | WO | claimed |