Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 9/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664584 | 0.84 | GSK3B (0.46) | GSK3BLMNAIDO1 | |
| SCHEMBL3665691 | 0.83 | GSK3B (0.45) | GSK3B | |
| SCHEMBL3654635 | 0.81 | GSK3B (0.46) | GSK3BALDH1A1KDM4EMAPT | |
| SCHEMBL1168937 | 0.80 | GSK3B (0.46) | GSK3BALDH1A1 | |
| SCHEMBL3662447 | 0.79 | GSK3B (0.45) | GSK3B | |
| SCHEMBL3659037 | 0.79 | GSK3B (0.43) | GSK3BLMNAKDM4E | |
| SCHEMBL3664250 | 0.78 | GSK3B (0.43) | GSK3BLMNAALDH1A1KDM4EMAPT | |
| SCHEMBL3662679 | 0.78 | GSK3B (0.44) | GSK3BALDH1A1 | |
| SCHEMBL3662330 | 0.77 | GSK3B (0.47) | GSK3B | |
| Hydrochloric Acid SCHEMBL3665578 | 0.76 | GSK3B (0.47) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238140-A2 | SUBSTITUTED HETEROARYLAMIDE DIAZEPINOPYRIMIDONE DERIVATIVES | Sanofi-Aventis (FR) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009095792-A2 | SUBSTITUTED HETEROARYLAMIDE DIAZEPINOPYRIMIDONE DERIVATIVES | SANOFI-AVENTIS (FR) | 2009-08-06 | — | — | WO | disclosed |