Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2368219 | 0.85 | MAOB (0.43) | CYP4F2CYP4A11KCNH2MAOBBCHE | |
| SCHEMBL28822312 | 0.81 | CETP (0.43) | CYP4F2CYP4A11TDP1KCNH2MAOB | |
| SCHEMBL13715411 | 0.80 | BCHE (0.42) | CYP4F2CYP4A11KCNH2MAOBTAAR1 | |
| SCHEMBL27733468 | 0.80 | CYP4F2 (0.70) | CYP4F2CYP4A11MAOBMGLLBCHE | |
| SCHEMBL27721818 | 0.77 | BCHE (0.49) | CYP4F2CYP4A11TDP1CHRM2CHRM1 | |
| SCHEMBL9621361 | 0.77 | CYP2D6 (0.53) | KCNH2PPARGPPARA | |
| SCHEMBL27825974 | 0.77 | KDM4E (0.48) | CYP4F2CYP4A11MAOBTAAR1CHRM2 | |
| SCHEMBL4737237 | 0.77 | TP53 (0.45) | MAOB | |
| SCHEMBL9442243 | 0.77 | MAOB (0.44) | TDP1KCNH2MAOB | |
| SCHEMBL177862 | 0.77 | TAAR1 (0.67) | TAAR1CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217598-A1 | NEW TETRACYCLIC COMPOUNDS | Medivation Technologies, Inc. (US) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009055828-A1 | NEW TETRACYCLIC COMPOUNDS | MEDIVATION TECHNOLOGIES, INC. (US) | 2009-04-30 | — | — | WO | disclosed |