Cyclopropane

Cyclopropane

SCHEMBL3663848

C1CC1.CC1OC(=O)C(C)OC1=O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.42
CA9 Q16790 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.39
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
TAS2R46 P59540 2/20 0.32
TDP1 Q9NUW8 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GMNN O75496 1/20 0.31
PPM1B O75688 1/20 0.31
LMNA P02545 1/20 0.31
PPP1CC P36873 1/20 0.31
TFPI2 P48307 1/20 0.31
RAB9A P51151 1/20 0.31
PPP5C P53041 1/20 0.31
PPP1CA P62136 1/20 0.31
PMP22 Q01453 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439067 0.90 CA1 (0.41) CA1CA9SMN1; SMN2KMT2AMEN1
SCHEMBL682255 0.90 CA1 (0.41) CA1CA9SMN1; SMN2KMT2AMEN1
SCHEMBL2860232 0.90 CA1 (0.41) CA1CA9SMN1; SMN2KMT2AMEN1
SCHEMBL15195848 0.90 CA1 (0.41) CA1CA9SMN1; SMN2KMT2AMEN1
SCHEMBL8104271 0.90 CA1 (0.41) CA1CA9SMN1; SMN2KMT2AMEN1
SCHEMBL44996 0.90 CA1 (0.41) CA1CA9SMN1; SMN2KMT2AMEN1
SCHEMBL732959 0.90 CA1 (0.41) CA1CA9SMN1; SMN2KMT2AMEN1
SCHEMBL15034 0.90 CA1 (0.41) CA1CA9SMN1; SMN2KMT2AMEN1
Methane SCHEMBL1276943 0.87 CA1 (0.39) CA1CA9SMN1; SMN2KMT2AMEN1
SCHEMBL15823554 0.87 CA1 (0.39) CA1CA9SMN1; SMN2KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7008429-B2 Bio-absorbable bone tie with convex head GOLOBEK DONALD D 2006-03-07 US claimed
WO-2006009558-A1 BIO-ABSORBABLE BONE TIE WITH CONVEX HEAD GOLOBEK DONALD D (US) 2006-01-26 WO claimed
US-20050288674-A1 BIO-ABSORBABLE BONE TIE WITH CONVEX HEAD GOLOBEK DONALD D 2005-12-29 US claimed
EP-2234545-B1 TISSUE LIGATION DEVICE RESORBABLE DEVICES AB (SE) 2016-01-06 EP disclosed
US-8696692-B2 Tissue ligation device VETOK AB (SE) 2014-04-15 US disclosed
US-20100292793-A1 TISSUE LIGATION DEVICE RESORBABLE DEVICES AB (SE) 2010-11-18 US disclosed
EP-2234545-A1 TISSUE LIGATION DEVICE Vetok AB (SE) 2010-10-06 EP disclosed
WO-2009091313-A1 TISSUE LIGATION DEVICE HOEGLUND ODD (SE) 2009-07-23 WO disclosed
US-7008429-B2 Bio-absorbable bone tie with convex head GOLOBEK DONALD D 2006-03-07 US disclosed
WO-2006009558-A1 BIO-ABSORBABLE BONE TIE WITH CONVEX HEAD GOLOBEK DONALD D (US) 2006-01-26 WO disclosed
US-20050288674-A1 BIO-ABSORBABLE BONE TIE WITH CONVEX HEAD GOLOBEK DONALD D 2005-12-29 US disclosed