Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | GYS1 | P13807 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1135918 | 0.99 | CHRM1 (0.40) | CHRM1MAOBHTR1AHTR7MAOA | |
| SCHEMBL3663890 | 0.97 | CHRM1 (0.39) | CHRM1MAOBHTR1AHTR7MAOA | |
| SCHEMBL1136185 | 0.87 | CHRM1 (0.41) | CHRM1MAOBHTR1AHTR7MAOA | |
| SCHEMBL13560282 | 0.87 | CHRM1 (0.39) | CHRM1MAOBHTR1AHTR7MAOA | |
| SCHEMBL2489841 | 0.87 | CHRM1 (0.39) | CHRM1MAOBHTR1AHTR7MAOA | |
| SCHEMBL17970287 | 0.86 | CHRM1 (0.41) | CHRM1MAOBHTR1AHTR7MAOA | |
| SCHEMBL15472265 | 0.86 | CHRM1 (0.43) | CHRM1MAOBHTR1AHTR7MAOA | |
| SCHEMBL2493908 | 0.86 | CHRM1 (0.39) | CHRM1MAOBHTR1AHTR7MAOA | |
| SCHEMBL2495645 | 0.86 | CHRM1 (0.41) | CHRM1MAOBHTR1AHTR7MAOA | |
| Hydrochloric Acid SCHEMBL13560351 | 0.86 | CHRM1 (0.39) | CHRM1MAOBHTR1AHTR7MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152699-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008150029-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2008-12-11 | — | — | WO | disclosed |