Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3079890 | 1.00 | S1PR1 (0.57) | S1PR1S1PR3 | |
| SCHEMBL3079876 | 1.00 | S1PR1 (0.57) | S1PR1S1PR3 | |
| SCHEMBL3088706 | 1.00 | S1PR1 (0.57) | S1PR1S1PR3 | |
| SCHEMBL3659277 | 0.91 | S1PR1 (0.56) | S1PR1S1PR3 | |
| SCHEMBL3079869 | 0.91 | S1PR1 (0.56) | S1PR1S1PR3 | |
| SCHEMBL3088479 | 0.91 | S1PR1 (0.56) | S1PR1S1PR3 | |
| SCHEMBL3079880 | 0.91 | S1PR1 (0.56) | S1PR1S1PR3 | |
| SCHEMBL3097577 | 0.90 | S1PR1 (0.54) | S1PR1S1PR3 | |
| SCHEMBL3073806 | 0.87 | S1PR1 (0.75) | S1PR1S1PR3 | |
| SCHEMBL3073802 | 0.87 | S1PR1 (0.75) | S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217594-A2 | NOVEL PYRIMIDINE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009057079-A2 | NOVEL PYRIMIDINE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2009-05-07 | — | — | WO | disclosed |