Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.84 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468541 | 0.96 | DHODH (0.78) | DHODH | |
| SCHEMBL468446 | 0.92 | DHODH (1.00) | DHODH | |
| SCHEMBL3667236 | 0.90 | DHODH (0.85) | DHODH | |
| SCHEMBL3668796 | 0.89 | DHODH (0.82) | DHODH | |
| SCHEMBL468664 | 0.86 | DHODH (0.76) | DHODH | |
| SCHEMBL468503 | 0.86 | DHODH (0.78) | DHODH | |
| SCHEMBL3664287 | 0.85 | DHODH (0.86) | DHODH | |
| SCHEMBL3670180 | 0.85 | DHODH (0.76) | DHODH | |
| SCHEMBL468575 | 0.83 | DHODH (1.00) | DHODH | |
| SCHEMBL2406359 | 0.82 | DHODH (0.59) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210615-A1 | Combinations comprising methotrexate and DHODH inhibitors | Almirall, S.A. (ES) | 2010-07-28 | — | — | EP | claimed |