Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | AAK1 | Q2M2I8 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31597704 | 1.00 | CA12 (0.47) | CA12CA1CA2CA9AAK1 | |
| SCHEMBL17957502 | 0.91 | PTGDR2 (0.53) | CA12CA1CA2CA9AAK1 | |
| SCHEMBL31078591 | 0.91 | CA12 (0.49) | CA12CA1CA2CA9AAK1 | |
| SCHEMBL2989527 | 0.90 | CA12 (0.46) | CA12CA1CA2CA9AAK1 | |
| SCHEMBL32055954 | 0.90 | CA12 (0.46) | CA12CA1CA2CA9AAK1 | |
| SCHEMBL26001198 | 0.88 | CA12 (0.50) | CA12CA1CA2CA9AAK1 | |
| SCHEMBL17958070 | 0.88 | PTPN11 (0.48) | CA12CA1CA2CA9IDO1 | |
| SCHEMBL38652880 | 0.87 | AAK1 (0.47) | CA12CA1CA2CA9AAK1 | |
| SCHEMBL31597645 | 0.87 | AAK1 (0.47) | CA12CA1CA2CA9AAK1 | |
| SCHEMBL20471909 | 0.87 | CA12 (0.46) | CA12CA1CA2CA9AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222669-B1 | OXADIAZOLE DERIVATIVES ACTIVE ON SPHINGOSINE-1-PHOSPHATE (SIP) | GLAXO GROUP LTD (GB) | 2013-08-21 | — | — | EP | disclosed |
| EP-2222669-A1 | OXADIAZOLE DERIVATIVES ACTIVE ON SPHINGOSINE-1-PHOSPHATE (SIP) | Glaxo Group Limited (GB) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009080725-A1 | OXADIAZOLE DERIVATIVES ACTIVE ON SPHINGOSINE-1-PHOSPHATE (SIP) | GLAXO GROUP LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |