Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468665 | 0.97 | DHODH (0.81) | DHODH | |
| SCHEMBL468419 | 0.93 | DHODH (1.00) | DHODH | |
| SCHEMBL3666606 | 0.89 | DHODH (0.87) | DHODH | |
| SCHEMBL468773 | 0.89 | DHODH (0.77) | DHODH | |
| SCHEMBL3665378 | 0.87 | DHODH (0.89) | DHODH | |
| SCHEMBL468584 | 0.86 | DHODH (0.81) | DHODH | |
| SCHEMBL468562 | 0.83 | DHODH (0.83) | DHODH | |
| SCHEMBL468508 | 0.82 | DHODH (1.00) | DHODH | |
| SCHEMBL3661258 | 0.82 | DHODH (0.67) | DHODH | |
| SCHEMBL468573 | 0.82 | DHODH (1.00) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210615-A1 | Combinations comprising methotrexate and DHODH inhibitors | Almirall, S.A. (ES) | 2010-07-28 | — | — | EP | claimed |