Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 10/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | HBB | P68871 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | EDNRA | P25101 | 1/20 | 1.00 |
| ▸ | HTR2A | P28223 | 1/20 | 1.00 |
| ▸ | RECQL | P46063 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.70 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.70 |
| ▸ | VCP | P55072 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | POLG | P54098 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acyclovir SCHEMBL2269160 | 1.00 | PNP (1.00) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL3175 | 1.00 | PNP (1.00) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL29531632 | 0.99 | PNP (0.97) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL16061083 | 0.99 | PNP (0.97) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL40724 | 0.99 | PNP (0.97) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL6239258 | 0.99 | PNP (0.97) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL16060281 | 0.99 | PNP (0.97) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL19031784 | 0.99 | PNP (0.97) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL1690304 | 0.99 | PNP (0.97) | PNPBLMHBBUSP2TSHR | |
| Acyclovir SCHEMBL29165535 | 0.97 | PNP (0.95) | PNPBLMHBBUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013187891-A1 | METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS | MARTIN ALAIN (US) | 2013-12-19 | — | — | WO | disclosed |
| EP-2187738-A1 | METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP OR DOWN REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS | Cellular Sciences, Inc. (US) | 2010-05-26 | — | — | EP | disclosed |
| WO-2009020582-A1 | METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP OR DOWN REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS | CELLULAR SCIENCES, INC. (US) | 2009-02-12 | — | — | WO | disclosed |