SCHEMBL3664909

SCHEMBL3664909

CCCCCc1ccc(N)c(CCCCC)c1N

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.43
SKP2 Q13309 1/20 0.42
CYP3A4 P08684 2/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
ALOX5 P09917 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
HTT P42858 1/20 0.41
KMT2A Q03164 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
TLR8 Q9NR97 2/20 0.39
LIPG Q9Y5X9 1/20 0.38
HTR2A P28223 1/20 0.37
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1498663 0.98 TYR (0.46) TYRSKP2CYP3A4MAPTMEN1
SCHEMBL1498626 0.94 SKP2 (0.47) TYRSKP2CYP3A4MAPTMEN1
SCHEMBL2400391 0.86 TYR (0.44) TYRSKP2CYP3A4MAPTMEN1
SCHEMBL2403029 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTMEN1
SCHEMBL1705721 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTMEN1
SCHEMBL1704787 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTMEN1
SCHEMBL1187291 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTMEN1
Bromide SCHEMBL5087885 0.85 TYR (0.43) TYRSKP2CYP3A4MAPTMEN1
SCHEMBL5424900 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTMEN1
SCHEMBL2400771 0.85 TYR (0.47) TYRSKP2CYP3A4MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9376551-B2 Cross-linked organosilicon polysulfides LANXESS DEUTSCHLAND GMBH (DE) 2016-06-28 US disclosed
US-20150191607-A1 Anti-fouling Paints and Coatings REACTIVE SURFACES, LTD (US) 2015-07-09 US disclosed
EP-2142496-B1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RES & ENG CO (US) 2013-04-17 EP disclosed
US-8080601-B2 Lubricating compositions containing ashless catalytic antioxidant additives EXXOMMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2011-12-20 US disclosed
EP-2142496-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES ExxonMobil Research and Engineering Company (US) 2010-01-13 EP disclosed
WO-2008121304-A1 LUBRICATING COMPOSITIONS CONTAINING ASHLESS CATALYTIC ANTIOXIDANT ADDITIVES EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-10-09 WO disclosed