Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.89 |
| ▸ | THRB | P10828 | 1/20 | 0.89 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decane SCHEMBL29490016 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Hexadecane SCHEMBL8539230 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Undecane SCHEMBL30872101 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Charcoal, Activated SCHEMBL31513512 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Heptane SCHEMBL1169629 | 1.00 | — | — | |
| Charcoal, Activated SCHEMBL30372643 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Dodecane SCHEMBL30601950 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Charcoal, Activated SCHEMBL31557734 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Tetradecane SCHEMBL7856354 | 1.00 | TSHR (0.89) | TSHRTHRBLMNADNM1ALDH1A1 | |
| Octane SCHEMBL29352390 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2242498-A2 | SYNERGISTIC ANTIPARASITIC COMPOSITIONS AND SCREENING METHODS | Tyratech, Inc. (US) | 2010-10-27 | — | — | EP | disclosed |
| WO-2009086471-A2 | SYNERGISTIC ANTIPARASITIC COMPOSITIONS AND SCREENING METHODS | TYRATECH, INC. (US) | 2009-07-09 | — | — | WO | disclosed |